Effectiveness of Panax ginseng root extract in cosmetics

Anti-aging: Aging is an inevitable natural law for human beings, and the free radical doctrine is generally recognized among the doctrines about aging. It has been found that Panax ginseng total saponin can increase the activity of endogenous antioxidant enzymes in the aging state, scavenge oxygen free radicals in the body, and delay aging from several aspects. Rg1 and Rb1 can significantly reduce the content of malondialdehyde, a peroxidation product in lipids, and have a strong inhibitory effect on lipid peroxidation, which has a certain delaying effect on aging.

Anti-inflammatory:

Researchers found that Panax notoginseng saponins Rg1 and Re contained in Panax notoginseng roots have significant inhibitory effects on the expression of iNOS inflammatory factors, and total Panax notoginseng saponins as well as Rd and Rb1 have good down-regulation effects on anti-inflammatory signaling pathways MAPK pathway and NF-κB pathway.

Panax ginseng polysaccharide can inhibit the expression of inflammatory leukocyte activating factor CSF2 and CSF1, and also can make the expression of negative intracellular signaling regulator TNF-AIP3 downregulated to indirectly inhibit the inflammation.

Skin repair: It was found that Panax ginseng saponin R1 could effectively promote the growth of granulation tissue at the edge of wounds, accelerate the formation of collagen fibers and thus promote skin wound healing.

In addition, Panax ginseng total saponin Ft1 promotes fibroblast proliferation and collagen synthesis through a signaling pathway, and Ft1 can promote the formation of neovascularization.

It was found that Panax notoginseng total saponin has in vitro anti-fibrotic effect and can treat human hyperplastic scar.